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How it works

Get to know more about the Orgonex way of working

We offer a smarter, more efficient alternative to traditional organoid culture. Our bioreactor technology is designed specifically for organoids, combining higher cell yields, reduced media costs, and minimal manual handling. With improved functionality, automation, and compatibility, we make advanced organoid culture accessible, scalable, and ready for the future.

Your easy lab solution

Bioreactor technology increased the efficiency for cell culture. However, until now no organoid-specific bioreactor existed. We provide a disruptive alternative to static cultures while increasing the cell yield and reducing the costs of culture media. Importantly, the functionality of the organoids is retained using stirred suspension cultures.

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What we do differently

Traditional static culture systems often fall short when it comes to supporting the complex needs of organoid development. Limited nutrient and gas exchange, uneven waste distribution, and labor-intensive processes can hinder both scalability and functionality. This is where dynamic bioreactor technology makes a difference. By introducing continuous stirring, this system creates a more controlled and supportive environment for organoid growth. Enhancing both efficiency and biological relevance.

Stirring

✔ Gas & nutrient exchange improved

✔ Better expansion

✔ Less involvement, more automation

✔ Retains or increases organoid function

✔ Waste products do not remain in near vicinity of the cells

✔ Gas & nutrient exchange improved

Static

❌ Bad exchange of nutrients and gasses

❌ Limited expansion of organoids

❌ Laborious process

❌ Organoid functionality remains low

❌ Unequal distribution of waste products

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The benefits

Costs reduction

The increased cell yield using the bioreactor will generate more cells over two weeks compared to static cultures. This will allow the use of less costly organoid media.

Automatization

Tired of all the manual labor involved in static organoid culture? The organoid bioreactor needs minimal attention and can be monitored without even opening the incubator.

Improved UX

With a control unit placed conveniently outside the incubator, the organoid culture can be monitored and only needs to be harvested once every two weeks. Simultaneous culture can be achieved with individual bioreactors (modular up to 32 bioreactors in sets of 4).

 

Compatibility

A tailor-made bioreactor for organoid culture, that is key to our technology. The RPMotion is compatible with most standard lab infrastructure.

Improved quality

More cells while remaining functional? We will provide the tools to efficiently expand organoids while retaining their functional state. It is all possible with the Orgonex bioreactor.

GMP compliance

Our bioreactor is ideal to aid in the production of a consistent product and is therefore an ideal combination for GMP compliance.

Any remaining questions?

Do not hesitate to send us a message.

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